Wolbachia

A large Wolbachia cluster found within the germline tissue of a Brugia pahangi nematode. This nematode was dissected from a Mongolian jird which had been treated with Rifampicin, a common antibiotic known to target Wolbachia. These large clusters of Wolbachia appear to be resistant to the antibiotic treatment. Actin is stained in green, host worm nuclei appear purple due to Propidium Iodide and DAPI double staining. Image Credit: Laura Chappell
Hypodermal chord structure of a Brugia pahangi parasitic nematode. Wolbachia can be seen as puncta surrounding host nematode nuclei. Green indicates the actin-rich structures of the nearby muscle cells. Wolbachia are found in only two places within the adult nematode: the female germline tissue and the male and female hypodermal chords. Image Credit: Laura Chappell
Early stages of infected D. mel ovaries stained with DAPI. CidA is one of two proteins responsible for Wolbachia induced Cytoplasmic incompatibility. CidA is bright in early stages of the ovaries but markedly absent in late stages. Image Credit: Jillian Porter
A) Salivary glands are stained with phalloidin (green) and DAPI (blue). B) Wolbachia is seen as small puncta among Drosophila salivary gland nuclei. Image credit: Sommer Fowler
The race to the pole: Wolbachia (mel) concentrate in the future germline at the posterior pole of the D. melanogaster oocyte (left). Wolbachia (Riverside) do not concentrate in the future germline of the D. simulans oocyte (middle). Wolbachia (mel) concentrate in the future germline of the D. simulans oocyte (right). Factors intrinsic to Wolbachia determine posterior germline localization.
A lesser known Jackson Pollock painting: 386-well plate seeded with Wolbachia infected cells used in our screens for new drugs to combat the neglected diseases, Elephantiasis and River Blindness.
Wolbachia (puncta) migration to and concentration at the posterior pole of a Jewel Wasp oocyte.
Contagion: Wolbachia invading the hypodermal chords of a filarial nematode.
Wolbachia associated with astral microtubules of a metaphase nucleus in the syncytial Drosophila embryo.
Wolbachia (puncta) concentrate around the centrosomes (dots) throughout the cell cycle.
Wolbachia (puncta) in developing Drosophila oocyte. Membrane separates the row of follicle cells from the oocyte cytoplasm. The large internal spheres are nurse cells and the smaller sphere is the oocyte nucleus. Image Credit: Alejandra Santiago

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